Microparticulate Caspase-1 Regulates Gasdermin-D and Pulmonary Vascular Endothelial Cell Injury.
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Abstract |
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Lung endothelial cell apoptosis and injury occurs throughout all stages of acute lung injury (ALI/ARDS) and impacts disease progression. Caspases 1, 4 and 5 are essential for completion of the apoptotic program known as pyroptosis that also involves pro-inflammatory cytokines. |
Year of Publication |
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2018
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Journal |
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American journal of respiratory cell and molecular biology
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Date Published |
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2018
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ISSN Number |
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1044-1549
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URL |
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http://www.atsjournals.org/doi/abs/10.1165/rcmb.2017-0393OC?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
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DOI |
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10.1165/rcmb.2017-0393OC
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Short Title |
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Am J Respir Cell Mol Biol
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