Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology.
| Author | |
|---|---|
| Abstract |
:
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia in the elderly population. In this study, we used the APP/PS1 transgenic mouse model to explore the feasibility of using diffusion kurtosis imaging (DKI) as a tool for the early detection of microstructural changes in the brain due to amyloid-β (Aβ) plaque deposition. |
| Year of Publication |
:
2018
|
| Journal |
:
Alzheimer's research & therapy
|
| Volume |
:
10
|
| Issue |
:
1
|
| Number of Pages |
:
1
|
| Date Published |
:
2018
|
| DOI |
:
10.1186/s13195-017-0329-8
|
| Short Title |
:
Alzheimers Res Ther
|
| Download citation |
