A new enzyme-linked immunosorbent assay for neurofilament light in cerebrospinal fluid: analytical validation and clinical evaluation.
| Author | |
|---|---|
| Abstract |
:
Cerebrospinal fluid (CSF) neurofilament light (NfL) is a reliable marker of neuro-axonal damage in different neurological disorders that is related to disease severity. To date, all recent studies performed in human CSF have used the same enzyme-linked immunosorbent assay (ELISA). To confirm the large body of evidence for NfL, we developed a new ELISA method and here we present the performance characteristics of this new ELISA for CSF NfL in different neurological disorders. |
| Year of Publication |
:
2018
|
| Journal |
:
Alzheimer's research & therapy
|
| Volume |
:
10
|
| Issue |
:
1
|
| Number of Pages |
:
8
|
| Date Published |
:
2018
|
| DOI |
:
10.1186/s13195-018-0339-1
|
| Short Title |
:
Alzheimers Res Ther
|
| Download citation |
