Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score.
| Author | |
|---|---|
| Abstract |
:
Treatment guidelines recommend a stepwise approach to primary biliary cholangitis: all patients begin treatment with ursodeoxycholic acid (UDCA) monotherapy and those with an inadequate biochemical response after 12 months are subsequently considered for second-line therapies. However, as a result, patients at the highest risk can wait the longest for effective treatment. We determined whether UDCA response can be accurately predicted using pretreatment clinical parameters. |
| Year of Publication |
:
2018
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| Journal |
:
The lancet. Gastroenterology & hepatology
|
| Volume |
:
3
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| Issue |
:
9
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| Number of Pages |
:
626-634
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| URL |
:
https://linkinghub.elsevier.com/retrieve/pii/S2468-1253(18)30163-8
|
| DOI |
:
10.1016/S2468-1253(18)30163-8
|
| Short Title |
:
Lancet Gastroenterol Hepatol
|
| Download citation |
