Preterm growth restriction and bronchopulmonary dysplasia: the vascular hypothesis and related physiology.
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Abstract |
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Approximately 5-10% pregnancies are affected by fetal growth restriction. Preterm infants affected by fetal growth restriction have a higher incidence of bronchopulmonary dysplasia. The present study is the first to measure pulmonary artery thickness and stiffness. The findings show that impaired vasculogenesis may be a contributory factor in the higher incidence of bronchopulmonary dysplasia in preterm growth restricted infants. The study addresses the mechanistic link between fetal programming and vascular architecture and mechanics. |
Year of Publication |
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2018
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Journal |
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The Journal of physiology
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Date Published |
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2018
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ISSN Number |
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0022-3751
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URL |
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https://doi.org/10.1113/JP276040
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DOI |
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10.1113/JP276040
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Short Title |
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J Physiol
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