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Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects.

Author
Abstract
:

The physiological challenges posed by hypobaric hypoxia warrant exploration of pharmacological entities to improve acclimatization to hypoxia. The present study investigates the preclinical efficacy of sphingosine-1-phosphate (S1P) to improve acclimatization to simulated hypobaric hypoxia.

Year of Publication
:
0
Journal
:
PloS one
Volume
:
9
Issue
:
6
Number of Pages
:
e98025
Date Published
:
2014
URL
:
http://dx.plos.org/10.1371/journal.pone.0098025
DOI
:
10.1371/journal.pone.0098025
Short Title
:
PLoS One
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