Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects.
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Abstract |
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The physiological challenges posed by hypobaric hypoxia warrant exploration of pharmacological entities to improve acclimatization to hypoxia. The present study investigates the preclinical efficacy of sphingosine-1-phosphate (S1P) to improve acclimatization to simulated hypobaric hypoxia. |
Year of Publication |
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0
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Journal |
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PloS one
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Volume |
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9
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Issue |
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6
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Number of Pages |
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e98025
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Date Published |
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2014
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URL |
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http://dx.plos.org/10.1371/journal.pone.0098025
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DOI |
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10.1371/journal.pone.0098025
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Short Title |
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PLoS One
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