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Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats.

Author
Abstract
:

Recent work has shown that the novel compound N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) may selectively block nicotinic acetylcholine receptors involved in regulating dopamine release. The current experiments examined the acute effect of bPiDDB on nicotine self-administration, sucrose-maintained responding, and nicotine-induced changes in acute and sensitized locomotor activity.

Year of Publication
:
2006
Journal
:
Psychopharmacology
Volume
:
184
Issue
:
3-4
Number of Pages
:
426-34
ISSN Number
:
0033-3158
URL
:
https://doi.org/10.1007/s00213-005-0163-8
DOI
:
10.1007/s00213-005-0163-8
Short Title
:
Psychopharmacology (Berl)
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