Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats.
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Abstract |
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Recent work has shown that the novel compound N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) may selectively block nicotinic acetylcholine receptors involved in regulating dopamine release. The current experiments examined the acute effect of bPiDDB on nicotine self-administration, sucrose-maintained responding, and nicotine-induced changes in acute and sensitized locomotor activity. |
Year of Publication |
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2006
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Journal |
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Psychopharmacology
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Volume |
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184
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Issue |
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3-4
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Number of Pages |
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426-34
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ISSN Number |
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0033-3158
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URL |
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https://doi.org/10.1007/s00213-005-0163-8
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DOI |
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10.1007/s00213-005-0163-8
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Short Title |
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Psychopharmacology (Berl)
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