Skip to main content

Effects of the mGluR2/3 receptor agonist LY379268 on the reinforcing strength of cocaine in rhesus monkeys.

Author
Abstract
:

Because chronic cocaine exposure produces profound effects on brain glutamate function, this system has been investigated as a target for novel medications for cocaine use disorder. Studies in animal models have provided encouraging results for drugs that target metabotropic glutamate receptors (mGluR), particularly group II mGluRs which includes mGluR2 and mGluR3 receptors.

Year of Publication
:
2020
Journal
:
Psychopharmacology
Volume
:
237
Issue
:
2
Number of Pages
:
409-417
ISSN Number
:
0033-3158
URL
:
https://dx.doi.org/10.1007/s00213-019-05377-y
DOI
:
10.1007/s00213-019-05377-y
Short Title
:
Psychopharmacology (Berl)
Download citation