Oxytocin in young children with Prader-Willi syndrome: Results of a randomized, double-blind, placebo-controlled, crossover trial investigating 3 months of oxytocin.
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Abstract |
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Prader-Willi syndrome (PWS) is characterized by hypothalamic dysfunction, hyperphagia and a typical behavioural phenotype, with characteristics of autism spectrum disorder (ASD) like stubbornness, temper tantrums and compulsivity. It has been suggested that the oxytocin system in patients with PWS is dysfunctional. In ASD, intranasal oxytocin treatment has favourable effects on behaviour. |
Year of Publication |
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2021
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Journal |
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Clinical endocrinology
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Volume |
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94
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Issue |
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5
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Number of Pages |
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774-785
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ISSN Number |
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0300-0664
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URL |
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https://doi.org/10.1111/cen.14387
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DOI |
:
10.1111/cen.14387
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Short Title |
:
Clin Endocrinol (Oxf)
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