Although the majority of adults will attempt to lose weight at some point in their lives, most weight loss behaviors are ineffective and potentially harmful. Further, weight loss behaviors often closely resemble disordered eating, and include behaviors such as fasting and purging. The current study examined potential predictors of disordered approaches to weight loss in the context of same-sex and opposite-sex romantic partnerships by investigating participants' (n = 500, M = 29.62 years) BMI, body image, self-esteem, relationship quality and disordered weight loss behaviors. We conducted analyses using Actor Partner Interdependence Models, which revealed that the greatest predictors of participating in disordered weight loss behavior were body dissatisfaction and having a male partner. These findings suggest that it is not sexuality, per se, that places individuals at risk for disordered weight loss behavior, but perhaps the value placed on thinness as defined by particular gender and cultural groups.