Mitochondrial uncoupler SHC517 reverses obesity in mice without affecting food intake.
| Author | |
|---|---|
| Abstract |
:
Mitochondrial uncouplers decrease caloric efficiency and have potential therapeutic benefits for the treatment of obesity and related metabolic disorders. Herein we investigate the metabolic and physiologic effects of a recently identified small molecule mitochondrial uncoupler named SHC517 in a mouse model of diet-induced obesity. |
| Year of Publication |
:
2021
|
| Journal |
:
Metabolism: clinical and experimental
|
| Volume |
:
117
|
| Number of Pages |
:
154724
|
| ISSN Number |
:
0026-0495
|
| URL |
:
https://linkinghub.elsevier.com/retrieve/pii/S0026-0495(21)00024-X
|
| DOI |
:
10.1016/j.metabol.2021.154724
|
| Short Title |
:
Metabolism
|
| Download citation |
