A novel quantitative trait locus on mouse chromosome 18, "era1," modifies the entrainment of circadian rhythms.
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Abstract |
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The mammalian circadian clock in the suprachiasmatic nuclei (SCN) of the hypothalamus conveys 24-h rhythmicity to sleep-wake cycles, locomotor activity, and other behavioral and physiological processes. The timing of rhythms relative to the light/dark (LD12:12) cycle is influenced in part by the endogenous circadian period and the time of day specific sensitivity of the clock to light. We now describe a novel circadian rhythm phenotype, and a locus influencing that phenotype, in a segregating population of mice. |
Year of Publication |
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2007
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Journal |
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Sleep
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Volume |
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30
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Issue |
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10
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Number of Pages |
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1255-63
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ISSN Number |
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0161-8105
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URL |
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https://academic.oup.com/sleep/article-lookup/doi/10.1093/sleep/30.10.1255
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DOI |
:
10.1093/sleep/30.10.1255
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Short Title |
:
Sleep
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