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Rearing environment differentially modulates cocaine self-administration after opioid pretreatment: A behavioral economic analysis.

Author
Abstract
:

Research has shown that previous experiences during development, especially if stressful, can alter an organism's response to opioids later in life. Given the previous literature on opioid modulation of cocaine self-administration, the current study raised rats in either an enriched condition (EC) or isolated condition (IC) and employed behavioral economics to study the effects of naltrexone and morphine on cocaine self-administration.

Year of Publication
:
2016
Journal
:
Drug and alcohol dependence
Volume
:
167
Number of Pages
:
89-94
Date Published
:
2016
ISSN Number
:
0376-8716
URL
:
https://linkinghub.elsevier.com/retrieve/pii/S0376-8716(16)30225-3
DOI
:
10.1016/j.drugalcdep.2016.07.026
Short Title
:
Drug Alcohol Depend
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