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Pattern of programmed cell death-ligand 1 expression and CD8-positive T-cell infiltration before and after chemoradiotherapy in rectal cancer.

Author
Abstract
:

The synergistic effect of combining immune checkpoint inhibitors with radiotherapy was reported recently, but there are few studies on programmed cell death-ligand 1 (PD-L1) expression in rectal cancer treated by preoperative chemoradiotherapy (CRT). The aim of the present study was to investigate the PD-L1 expression status before and after CRT and its association with clinicopathological characteristics and recurrence in rectal cancer.

Year of Publication
:
2018
Journal
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European journal of cancer (Oxford, England : 1990)
Volume
:
91
Number of Pages
:
11-20
Date Published
:
2018
ISSN Number
:
0959-8049
DOI
:
10.1016/j.ejca.2017.12.005
Short Title
:
Eur J Cancer
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